List of all CardiolPlus ingredients®

How CardiolPlus ingredients® can help with:

High cholesterol

High blood pressure

Thrombus formation

Cholesterol

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Policosanol

Policosanol is a natural supplement isolated from sugarcane wax. It consists of a mixture of long-chain aliphatic alcohols, with octacosanol being the most abundant. It is effective in reducing blood cholesterol levels. A randomized, double-blind, placebo-controlled study in 589 patients showed that a daily dose of 5–10 mg of policosanol over one year had a favorable effect on reducing “bad” LDL cholesterol and slightly increasing “good” HDL cholesterol. One CardiolPlus® One sachet provides exactly the optimal daily dose of 20 mg of policosanol for full support of the body.

Nattokinase

Nattokinase is an enzyme obtained by soybean fermentation and is best known for its fibrinolytic and antithrombotic effects. It also shows an effect on lipid status by reducing total and LDL cholesterol through decreased endogenous cholesterol synthesis, and it leads to a mild reduction in triglycerides, especially in individuals with insulin resistance. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of nattokinase for full support of the body.

Dry pine extract

Dry pine extract has clinical evidence showing that it mildly to moderately reduces total and LDL cholesterol and is particularly effective in individuals with type 2 diabetes, metabolic syndrome, and oxidative stress. In people with diabetes and insulin resistance, it leads to a moderate reduction in triglyceride levels. One CardiolPlus® sachet provides exactly the optimal daily dose of 10 mg of extract per day for full support of the body.  

Amla (Emblica officinalis)

Amla (Emblica officinalis) has a well-documented and clinically significant effect on lipid status, especially in dyslipidemia, type 2 diabetes, and metabolic syndrome. Among herbal supplements, it is one of the most effective options, as it reduces total and LDL cholesterol through inhibition of HMG-CoA reductase and increased expression of LDL receptors, and it also has strong antioxidant activity. At the same time, it significantly lowers triglycerides and leads to a moderate increase in HDL. Due to its additional cardiometabolic effects, it is an excellent choice when dyslipidemia is accompanied by elevated blood sugar, abdominal obesity, and early atherosclerosis. One CardiolPlus® sachet provides exactly the optimal dose of 50 mg of amla for full support of the body.  

Dry olive leaf extract

Dry olive leaf extract has a clinically significant effect on lipid status, with its advantage being combined cardiovascular and metabolic activity. Studies show mild to moderate reductions in total cholesterol and LDL cholesterol, especially in early hypercholesterolemia. It also leads to a slight increase in HDL and may moderately reduce triglycerides. Additional effects of olive leaf polyphenols include reducing the atherogenic effect of LDL, exerting anti-inflammatory and antioxidant activity, and improving insulin sensitivity. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of extract for full support of the body.

Blood pressure

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Nattokinase

Nattokinase is known for its unique effect on blood vessels and blood pressure by breaking down fibrin, a protein involved in the formation of blood clots. Many studies indicate the effectiveness of nattokinase. In a randomized, double-blind, placebo-controlled study in 86 adult patients with mildly elevated blood pressure, taking 2000 FU (100 mg) of nattokinase daily for 8 weeks led to a reduction in both systolic and diastolic blood pressure. Just one CardiolPlus® sachet delivers the full potential of nattokinase in the optimal dose of 2000 FU – naturally, conveniently, and effectively.

Policosanol

Policosanol is a natural supplement obtained from sugarcane wax. A meta-analysis of 19 studies involving 2,300 patients examining the effects of policosanol on blood pressure showed reductions in systolic and diastolic pressure, especially in patients with prehypertension, after 12 weeks of use. At the same time, by reducing LDL cholesterol and improving blood vessel function, it leads to a mild improvement in vascular tone, which further contributes to blood pressure reduction. One CardiolPlus® sachet provides exactly the optimal daily dose of 20 mg of policosanol for full support of your body.

Dry grape seed extract

Dry grape seed extract contains proanthocyanidins as its main components, which are powerful antioxidants. They improve endothelial cell function and increase nitric oxide (NO) production, leading to blood vessel dilation. They also reduce oxidative stress and inflammation in blood vessels, which can indirectly affect blood pressure. Studies show reductions in systolic and diastolic blood pressure in individuals with mildly elevated blood pressure. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of extract per day – for full support of cardiovascular health.

Dry pine bark extract

Dry pine bark extract has a clinically proven positive effect on blood pressure, especially in individuals with mild to moderate hypertension. It works by improving endothelial function and blood vessel elasticity, reducing inflammation, and exerting strong antioxidant effects. The effect is more pronounced in people with high blood pressure, type 2 diabetes, and metabolic syndrome. One CardiolPlus® sachet provides exactly the optimal daily dose of 10 mg of extract per day – for full support of cardiovascular health.

Dry amla fruit extract

Dry amla fruit extract helps lower blood pressure and supports blood vessel health. The effect is more pronounced in individuals with hypertension, dyslipidemia, insulin resistance, and diabetes. Amla improves endothelial function and stimulates nitric oxide (NO) production, contributing to blood vessel dilation. Amla is a powerful antioxidant, reduces oxidative stress and inflammation, and also has a mild diuretic effect. One CardiolPlus® sachet provides exactly the optimal daily dose of 50 mg of extract per day – for full support of cardiovascular health.

Dry olive leaf extract

Dry olive leaf extract has proven antihypertensive effects and is among the best-studied herbal supplements for lowering blood pressure. The main active compound is oleuropein, along with hydroxytyrosol and flavonoids. Its actions include blood vessel dilation (increased NO), ACE enzyme inhibition, reduction of oxidative stress and inflammation, improvement of arterial elasticity, and a mild diuretic effect. In some studies, olive leaf extract has shown effects comparable to mild antihypertensive drugs in untreated patients. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of extract per day – for full support of cardiovascular health.

Dry shilajit (mumijo) extract

Dry shilajit (mumijo) extract has adaptogenic and toning effects, while its influence on blood pressure is indirect. It may improve endothelial function. In individuals with high blood pressure caused by stress or fatigue, it may lead to a mild reduction. It mildly improves the lipid profile, positively affects blood sugar regulation, and contributes to better exercise tolerance.

Magnesium

Magnesium is among the most important minerals for regulating vascular tone and heart function. Meta-analyses of clinical studies show an average reduction in systolic blood pressure of up to 5 mmHg and diastolic pressure of up to 4 mmHg. Magnesium relaxes the smooth muscles of blood vessels, leading to arterial dilation. It acts as a natural calcium antagonist, improves endothelial function and increases nitric oxide (NO), reduces sympathetic nervous system activity, and may mildly improve insulin sensitivity.

Thrombus formation

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Nattokinase

Nattokinase is a fibrinolytic enzyme, which means it does not act directly as an antiplatelet agent but instead breaks down fibrin, the main protein in blood clots. In this way, it dissolves already formed thrombi and can improve blood flow. It acts similarly, though somewhat more mildly, than thrombolytics used in emergency cases of thrombosis. Nattokinase reduces thrombin activity and thereby indirectly decreases the ability to form new clots. It does not significantly affect platelet count, but by reducing thrombin activity it may slightly reduce their role in clotting. The fibrinolytic and anticoagulant effects of nattokinase contribute to improved circulation and the prevention of thrombosis. One CardiolPlus® sachet provides exactly the optimal dose of 100 mg of nattokinase extract – for full support of your cardiovascular health.

Policosanol

Policosanol is a mixture of alcohols isolated from sugarcane wax. In a randomized, double-blind, placebo-controlled study involving 90 participants, policosanol at a dose of 20 mg per day for 4 weeks contributed to the prevention of platelet accumulation and thus the formation of blood clots. Policosanol shows a clinically significant effect on the inhibition of platelet aggregation. Policosanol (20 mg) exhibits the same efficacy as aspirin (100 mg). One CardiolPlus® sachet provides exactly the optimal daily dose of 20 mg of policosanol for full support of your body.

Grape seed extract

Grape seed extract has a mild to moderate antiplatelet effect, which is clinically significant mainly in individuals with increased cardiovascular risk or when combined with other antiplatelet agents. Its active components, proanthocyanidins, reduce platelet activation, inhibit aggregation induced by ADP, collagen, and epinephrine, reduce oxidative stress in platelets, and improve endothelial function. It is most useful as a complementary preventive option alongside other anti-aggregation substances. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of extract per day – for full support of cardiovascular health.

Pine bark extract

Pine bark extract has a mild to moderate antiplatelet effect that is stronger than that of most other plant antioxidants. It shows a clinically significant effect by reducing platelet aggregation induced by ADP, collagen, and epinephrine. Unlike aspirin, it works without direct COX-1 inhibition and therefore does not cause complete platelet inhibition. The effect appears after 2–4 weeks of regular use. One CardiolPlus® sachet provides exactly the optimal daily dose of 10 mg of extract per day – for full support of cardiovascular health.

Dry olive leaf extract

Dry olive leaf extract has an effect on reducing platelet aggregation and thus acts protectively on the cardiovascular system, especially as an adjunct to medications that affect blood clotting. One CardiolPlus® sachet provides exactly the optimal daily dose of 100 mg of extract per day – for full support of your cardiovascular health.

How do vitamins and minerals help?

Vitamin B1

In the formulation of CardiolPlus® acts synergistically with the other ingredients. It plays a key role in metabolism of carbohydrates and in energy production for the normal functioning of the heart as an organ that works continuously. It is also important for maintaining a normal heart rhythm and contributes to better regulation of blood vessel tone.It is particularly important for certain groups of patients – those with heart failure, people with diabetes, those using diuretics, and older adults.

Vitamin C

It has a significant protective role for the heart and blood vesselsespecially by acting on the endothelium (the vessel wall), by stimulating collagen production and improving their elasticity.Thereby reducing the risk of atherosclerosis as well as the tendency for thrombus formation. Clinical studies show that vitamin C may have a moderate effect on lowering blood pressure, especially in individuals with mild hypertension, and thanks to its antioxidant effect, it neutralizes free radicals and prevents the formation of LDL (bad) cholesterol.

Vitamin D3

A dose of 800 IU/d contained in the CardiolPlus formulation® is is a physiological, safe, and rational supportive dose that acts synergistically with the other ingredients.The effect is more pronounced in individuals with vitamin D3 deficiency. Lower vitamin D3 levels are associated with impaired heart function and a higher risk of heart failure. The most important effects on the cardiovascular system include improved endothelial function because it contributes to arterial elasticity and better blood flow.. In this way acts indirectly on lowering blood pressure.

Magnesium – lactate

One of the key minerals for heart health. Supports vascular tone acting as a natural relaxant, regulates heart rhythm, reduces the tendency toward thrombosis and improves stress response. The lactate form is highly soluble and gentle on the digestive tract, making it suitable for daily, long-term use in the CardiolPlus supplement®.

Potassium

Very important for the normal function of the heart and blood vessels. It is essential for the proper generation and transmission of impulses in the heart muscle, thereby maintaining heart rhythm. It is especially important for people with heart failure and those on diuretic therapy. Potassium lowers blood pressure by increasing sodium excretion through the kidneys, reducing fluid retention, and causing blood vessel dilation. Studies show that potassium intake reduces the risk of coronary heart disease, hypertension, and stroke.